Why 70 Percent Alcohol Disinfects Better Than 91 Percent, According to a Microbiologist (2024)

Ashley Abramson

Ashley Abramson

Ashley Abramson is a writer-mom hybrid. Her work, mostly focused on health, psychology, and parenting, has been featured in the Washington Post, New York Times, Allure, and more. She lives in the Milwaukee suburbs with her husband and two young sons.

updated Nov 1, 2022

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When you’re worried about getting sick, it’s natural to bring out the big guns, like bleach or rubbing alcohol. Both of these products are effective at disinfecting your surfaces, but did you know there’s a counter-intuitive rule of thumb to follow when you clean with alcohol? It has to do with the percentage of alcohol by volume.

You would think alcohol solutions with a higher percentage would be more powerful at killing germs on your high-touch items like phones and doorknobs, right? A lower percent alcohol means there’s more water diluting the mix in the bottle. But according to microbiology, 70 percent alcohol is probably more effective than 91 percent for disinfecting—depending on what kind of germs you’re trying to kill.

Here’s why lower-percentage alcohol might be a better weapon against germs:

According to Dr. Elizabeth Scott, professor of microbiology at Simmons Center for Hygiene and Health in Home and Community at Simmons University in Boston, higher-percentage alcohols are more concentrated. That means lower percentages, like 70 percent, have more water in them. Turns out, the water is actually an important ingredient here.

Basically, a 90 or 91 percent alcohol solution is too powerful in some cases: It fries the outside of the cell before it can get into the inside and kill the actual germ. 70 percent alcohol is just the right proportion of water and alcohol to zap the entire cell.

“Seventy percent alcohol has some water in it that allows it to cross a cell membrane, to really get into the bacteria to kill them,” Scott says.

Interestingly, Scott explains this rule of thumb only applies when you’re attempting to fend off bacteria. Alcohol’s effectiveness against viruses depends on the unique virus.

Viruses with an envelope structure — including the flu virus, the common cold, HIV, and SARS-CoV-2 (the virus that causes COVID-19) — can be deactivated by alcohol solutions (like hand sanitizer) of 60 percent or more, while others like norovirus won’t be effectively targeted by any concentration of alcohol. (Hand-washing helps to physically remove every type of virus and bacteria from your hands and is an important part of any hygiene routine.)

Practically, how does this rule of thumb apply to home hygiene? If you’re cutting raw chicken on the counter and want to effectively disinfect the surface to prevent cross-contamination of E. coli and salmonella bacteria, you’d want to opt for 70 percent alcohol. But if you’re trying to disinfect a surface that might have viruses lingering on it — for example, if someone in your house has the flu — any dilution of alcohol will work as long as it’s above the recommended 60 percent.

In any case, it’s important to focus on hygiene practices like thorough hand washing (20 seconds of scrubbing each time!) and targeted hygiene (regularly disinfecting high-traffic hand-contact areas in your home, especially if someone sick has touched them). Stay healthy!

Why 70 Percent Alcohol Disinfects Better Than 91 Percent, According to a Microbiologist (2024)

FAQs

Why 70 Percent Alcohol Disinfects Better Than 91 Percent, According to a Microbiologist? ›

Pingback: TIL that 70% isopropyl alcohol is more effective at killing bacteria than 91% alcohol. This is because the water in the solution helps it permeate more fully.

Why is 70 percent alcohol a better disinfectant? ›

Even though you may think the higher concentration is more effective, experts say 70% is actually better for disinfecting. It has more water, which helps it to dissolve more slowly, penetrate cells, and kill bacteria.

Why is 70% alcohol was used in microbiology? ›

Experiments have shown that for most bacteria, 70% ethanol is much better for killing them. Rather use 70%.

What is the difference between 70 and 91 isopropyl alcohol? ›

With 91% IPA, the evaporation is instant and protein coagulates, rendering the effect of the IPA greatly reduced. This means that 91% IPA takes a greater time to act and doesn't kill as much bacteria as 70% IPA. The latter is also cheaper.

Why is 70% the most effective concentration of denatured ethanol for disinfection? ›

At a 70% concentration, however, the ethanol takes longer to evaporate and this longer contact time means that it is able to penetrate cells more effectively. The water in a 70% grade is also important in denaturing proteins.

Does 91 percent alcohol disinfect? ›

The Centers for Disease Control and Prevention (CDC) recommends an alcohol concentration of between 60 and 90 percent for disinfection purposes.

Why 70% ethyl alcohol is better antiseptic than 95% ethanol solution? ›

Answer and Explanation:

The 70% ethanol solution has a higher contact time with the skin, while a 95% ethanol solution tends to dry up more rapidly (i.e., a lower contact time). Since a 70% ethanol solution has more water, it takes longer to dissolve and thus can actually penetrate the bacterial cell wall and kill it.

Why do we clean the bench top with 70% alcohol before we start our work? ›

Why do we clean the bench top with 70% alcohol BEFORE we start our work? This level of concertation kills all the bacteria that could be on the work bench and because of the water content it slows the evaporation time making it more effective.

What is the best alcohol for disinfecting? ›

Ethyl alcohol (70%) is a powerful broad-spectrum germicide and is considered generally superior to isopropyl alcohol.

Does 70 or 91 alcohol burn faster? ›

Isopropyl alcohol (rubbing alcohol) is an acceptable cooking fuel. It may be purchased in 70 percent, 91 percent. The higher the percentage of alcohol, the better the alcohol will burn.

What is the purpose of 91% isopropyl alcohol? ›

Uses. first aid to help prevent the risk of infection in minor cuts, scrapes and burns.

What is the limitation of using 70% ethanol as a primary surface disinfectant? ›

70% Ethanol

Aqueous alcohol solutions are not appropriate for surface decontamination because of the evaporative nature of the solution; a contact time of ten minutes or more is necessary and not achievable using a 70% (v/v) aqueous solution of ethanol.

Which concentration of ethanol is the most effective as a disinfectant? ›

It is demonstrated in Table ​3 that a safe bactericidal effect of ethanol, including inactivation of vegetative forms of spores, is given in concentrations of 60%–85%, with the optimal effective concentration being 80%–85%.

How is 70% ethanol prepared as a disinfectant? ›

Alcohols can be used on skin, work surfaces of laboratory benches. To prepare 1 liter of 70% Ethanol using 95% lab Ethanol add 740ml of lab ethanol to 260ml water.

Is 70 or 91 isopropyl alcohol better? ›

IPA is inexpensive and effective. Pingback: TIL that 70% isopropyl alcohol is more effective at killing bacteria than 91% alcohol. This is because the water in the solution helps it permeate more fully.

Why 70% alcohol is better disinfectant than 100% alcohol? ›

First, it has been found to be more effective at killing microorganisms than higher concentrations of isopropyl alcohol. This is because the water content in the 70% IPA solution allows for better penetration into the microorganisms and denaturation of proteins.

How do you disinfect with 70% alcohol? ›

Be sure to use a rubbing alcohol product that contains at least 70 percent isopropanol. Don't dilute rubbing alcohol with water. First, wash the surface you wish to disinfect with soap and water. Then use a wipe, towel, or spray bottle to evenly apply the rubbing alcohol to the surface.

What percentage of alcohol is the most effective disinfectant quizlet? ›

Ethyl alcohol is the exception. Very effective disinfectant and antiseptic. Most effective at 70%. Combination of 70% ethanol and 30% water is more effective than 100%.

Is 70 alcohol good for cleaning electronics? ›

You can use 70%, 91%, or 99% isopropyl alcohol to clean various types of electronics – what you choose will depend on what you're cleaning. For externals – such as disinfecting your smartphone or TV remote – 60-70 percent will do a better job.

What is 50% isopropyl alcohol used for? ›

Isopropyl alcohol (50% conc.) decrease germs in minor cuts and scrapes. helps relieve minor muscular aches due to exertion.

Does 70% isopropyl alcohol leave a residue? ›

It leaves no residue, evaporates quickly relative to water, and does not cause corrosion.

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