Drug Price - Depin (5mg) - 50 Capsule (Nifedipine) (2024)

Information Checked by - Dr. M. Sree Mohana Preetha, Pharm D

Further Checked by - Dr. M. Janani Priya, Pharm D

Nifedipine (Depin (5mg)) is a calcium channel blocker, prescribed for angina (chest pain), high blood pressure and abnormal heart rhythms. It works by relaxing blood vessels.

The information provided on this page is intended to serve as a comprehensive resource and should not be a substitute to professional medical advice. If you have concerns it is always best to speak with a healthcare professional.

The information provided on this page is intended to serve as a comprehensive resource and should not be a substitute to professional medical advice. If you have concerns it is always best to speak with a healthcare professional.

Substitute/Alternative Medication to Depin (5mg)

When is Depin (5mg) prescribed?

It is prescribed for -

⇨ Chest Pain

Drug Price - Depin (5mg) - 50 Capsule (Nifedipine) (2024)

FAQs

Is nifedipine a good blood pressure medication? ›

If you have high blood pressure, taking nifedipine helps to prevent future heart disease, heart attacks and strokes. Nifedipine is also used to prevent chest pain caused by angina. Occasionally, it's used to treat Raynaud's phenomenon and chilblains.

What should you avoid when taking nifedipine? ›

Is there any food or drink I need to avoid? Do not eat grapefruit or drink grapefruit juice. This is because grapefruit can increase the amount of nifedipine in your body, and cause side effects such as headache, flushing and feeling dizzy or faint.

Why is nifedipine no longer used? ›

Nifedipine, a dihydropyridine calcium channel blocker, was once one of the most widely used medications for hypertension, but safety and tolerability concerns along with the introduction of new classes of antihypertensive medications and an increasing pool of data showing mortality benefit of other classes caused ...

How long does it take nifedipine to lower blood pressure? ›

Nifedipine has a rapid onset of action (buccal, 10-15 minutes; oral, 30-45 minutes) and peak effect (buccal, 30 minutes, oral, 60 minutes). The duration of effects is four to six hours regardless of the route of administration, with a mean arterial pressure reduction of 21.6% (248/134 mm Hg to 165/87 mm Hg).

What drug is better than nifedipine? ›

Amlodipine was better tolerated than nifedipine, as shown by the lower incidence of side effects.

Is nifedipine safe for kidneys? ›

First generation CCBs, like nifedipine, act exclusively on L-type calcium channels, and predominantly dilate afferent arterioles with the danger of glomerular hypertension and subsequent harm of the renal microcirculation.

What are the two worst blood pressure medications? ›

5 of the worst blood pressure medications
  1. Beta blockers. Usually, beta blockers aren't used as first-choice therapies to lower blood pressure. ...
  2. Loop diuretics. Furosemide (Lasix) is a type of diuretic (water pill) known as a loop diuretic. ...
  3. Alpha blockers. ...
  4. Vasodilators. ...
  5. Alpha-2 agonists.
Feb 14, 2024

What is the safest high blood pressure medication to take? ›

Which medications are safe for high blood pressure?
  • ACE inhibitors (benazepril, zofenopril, lisinopril, and others)
  • angiotensin II receptor blockers (losartan and valsartan)
  • beta-blockers (acebutolol, atenolol, bisoprolol, and others)
  • calcium channel blockers (amlodipine and diltiazem)
Oct 25, 2023

What is the danger of nifedipine? ›

This medicine may cause fluid retention (edema) in some patients. Tell your doctor right away if you have bloating or swelling of the face, arms, hands, lower legs, or feet; tingling of the hands or feet; or unusual weight gain or loss. Do not stop taking this medicine without first checking with your doctor.

What vitamins should not be taken with nifedipine? ›

Interactions with Nifedipine
  • Calcium.
  • Coenzyme Q10.
  • Ephedra.
  • Magnesium.
  • Melatonin.
  • Vitamin D.

Can I drink coffee while on nifedipine? ›

Speak to a doctor if the dizzy feelings last for more than a couple of days. This usually happens when you first start taking nifedipine. Try cutting down on coffee, tea and alcohol. If the flushing is also making you feel hot, it might help to keep the room cool and use a fan.

Who cannot take nifedipine? ›

have ever had an allergic reaction to nifedipine or any other medicine. have liver disease. have any heart problems (other than high blood pressure), including a recent heart attack, heart failure or unstable angina. have diabetes.

What is the most common side effect of nifedipine? ›

Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position. These symptoms are more likely to occur when you begin taking this medicine, or when the dose is increased. This medicine may cause fluid retention (edema) in some patients.

Is nifedipine stronger than lisinopril? ›

In conclusion, lisinopril and nifedipine are both effective in reducing blood pressure in patients with mild to severe hypertension. Lisinopril qd and nifedi pine slow release bid produce similar decreases in blood pressure after twelve weeks of therapy and the safety profiles of the two drugs are similar.

How much does nifedipine lower BP? ›

Results: Even 18 to 24 hours after administration, the systolic blood pressure was reduced on average by 20 mmHg, the diastolic pressure by 14 mmHg.

Is nifedipine better than metoprolol? ›

Keep in mind the nifedipine IR is rarely prescribed. Some side effects of nifedipine include swelling in the legs, dizziness, tiredness, and headache. Metoprolol tartrate (Lopressor) is used to treat chest pain and high blood pressure. It's also used to lower the risk of death after a heart attack.

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