Genetics helps to explain:
What makes you unique, or one of a kind
Why family members look alike
Why some diseases like diabetes or cancer run in families
How learning your family health history can help you stay healthy
Why you should bring your family health history to your healthcare provider
Taking time to learn about health and diseases that run in your family is worth it! Itwill help you understand your own health and make healthy choices.
What makes me unique?
Every person is unique. Part of what makes you unique is your genes. Genes are theinstructions inside each of your cells. They control how you look and how your bodyworks. Since everyone has slightly different genes, everyone has a different set ofinstructions. Genes are one reason why you are unique!
Tell me more about my genes
A person has two copies of each gene, one from the mother and one from thefather.
Genes carry instructions that tell your cells how to work and grow.
Cells are the building blocks of the body. Every part of your body is made upof billions of cells working together.
Genes are arranged in structures called chromosomes. Humans have 23 pairs ofchromosomes. Copies of the chromosomes are found in each cell.
Chromosomes are made up of DNA. DNA is the special code in which theinstructions in your genes are written.
Why do family members have things in common?
Children inherit pairs of genes from their parents. A child gets one set of genesfrom the father and one set from the mother. These genes can match up in many waysto make different combinations. This is why many family members look a lot alike andothers don’t look like each other at all. Genes can also increase the riskin a family for getting certain health conditions.
Families also share habits, diet, and environment. These influence how healthy we arelater in life.
You share a lot with your family—including what can make you sick.
Why do some diseases run in families?
Some diseases are caused when there is a change in the instructions in a gene. Thisis called a mutation. Every person has many mutations. Sometimes these changes haveno effect or are even slightly helpful. But sometimes they can cause disease.
Most common diseases are caused by a combination of mutations, lifestyle choices, andyour environment. Even people with similar genes may or may not get an illness ifthey make different choices or live in a different environment.
Thousands of diseases are caused by a specific change in the DNA of a single gene.Many of these diseases are rare. These conditions usually develop when an individualis born with a mutated gene.
If a rare disease runs in your family, be sure to write it down. Do not forget tolearn about common conditions that affect your family’s health.
Visit page 10 to learn about some diseases that run in families.
Common Disease: Diabetes
Changes in your genes passed on by your parents may make you more likely todevelop type 2 diabetes. If you are active and eat a healthy diet, you may beable to lower your risk.
Single Gene Disorder: Sickle Cell Anemia
Sickle cell anemia is caused by a mutation in a single gene passed from eachparent.
How can family health history help me stay healthy?
Your family health history tells you which diseases run in your family. Healthproblems that develop at a younger age than usual can be a clue that your family hasa higher risk. Though you cannot change your genes, you can change yourbehavior.
Knowing your family health history will help you:
Identify risks due to shared genes.
Understand better what lifestyle and environmental factors you share withyour family.
Understand how healthy lifestyle choices can reduce your risk ofdeveloping a disease.
Talk to your family about your health.
Tell your healthcare provider about the diseases that run in your family.
Remember
- 1.
Share your family health history with your healthcare provider.
- 2.
Ask if you can be screened for a disease that runs in your family.
Why should I bring my family health history to my healthcare provider?
Your healthcare provider (doctor, nurse, or physician’s assistant) may useyour family health history and current health to figure out your risk for developinga disease. Your provider can then help decide which screenings you get and whichmedicines you might take.
Based on your family health history, a healthcare provider may order a genetic testor refer you to a genetic counselor or geneticist. Genetic tests can show if youhave a gene change that increases your risk for disease. They can also tell if youhave a gene change that you might pass on to your children. Your healthcare providercan help you:
Understand the results of your tests.
Learn of any treatments for a disease found by the test.
All newborn babies born in the U.S. and many other countries are tested for certaingenetic diseases that may make them sick. This is called newborn screening. If thescreening test finds a problem, a healthcare provider will help you understand whatcan be done to help the baby.
