I guess that at the simplest level, Defender for Cloud will help protect your Cloud (Azure) workloads (although it can also track and protect some outside resources) whereas Defender for Endpoint protects your devices (Windows clients, but also other platforms).
As part of Defender for Cloud, you can select Defender for Servers either at the Premium 1 (P1) or Premium (P2) level.
Then, Defender for Office 365 protects your Microsoft 365 data (Exchange mailboxes, SharePoint sites and Teams...), Defender for Identity protects your onsite Active Directory and Defender for Cloud Apps help track and protect your users when navigating the Internet.
I hope the above helps.
Kosala Randika Paranathala 76Reputation points
2023-03-31T13:39:57.5733333+00:00 Hi,
Thank you for your reply, we have doubts about which defender portal should use to install for our on-premise servers. Since our Win 10 computers have been enrolled in defender for endpoint and managing via Intune portal. Another question do we need to use Azure Arc for this. I am worried about our license already purchased. Since it is via Azure portal.
Marc Michault 5Reputation points
2023-03-31T16:47:35.79+00:00 As per the "Plan agents, extensions, and Azure Arc for Defender for Servers" article, the "Review Azure Arc requirements", Azure Arc is necessary and under "Defender for Endpoint extensions", the Defender for Endpoint extension will be deployed by Defender for Servers.
I should warn that have not tested those myself (and thus cannot warn of any gotchas or if there are workarounds) and that my response is solely based on articles your can research yourself: Test it out before committing.
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