Gabapentin for Dogs: How It Can Help (2024)

Gabapentinhas a variety of uses in veterinary medicine, and prescribing gabapentin for dogs, especially, is becoming more popular amongst veterinarians.

Here’s everything you need to know about gabapentin for dogs.

Key Takeaways

  • Veterinarians commonly prescribe gabapentin to treat pain, seizures, and anxiety in dogs.
  • Gabapentin is a human medication, and its use in veterinary medicine is “off-label,” meaning it is not FDA-approved for pets.
  • Sedation is the main potential side effect of gabapentin, and the level of sleepiness varies from patient to patient.

What Is Gabapentin for Dogs?

Gabapentin is an anticonvulsant and analgesic drug that is commonly prescribed by veterinarians to treat pain, seizures, andanxiety in dogs.

How gabapentin works is not completely understood; however, it is thought to block stimulation of the nerve cells.

What Is Gabapentin Used for in Dogs?

Gabapentin is a human medication, and its use in veterinary medicine is “off-label,” meaning it is not FDA-approved for pets. But gabapentin can be prescribed to help with pain, seizures, and anxiety in dogs.

Preventing Seizures

Gabapentin has anticonvulsant properties that make it beneficial for adjunctive therapy for dogs with refractory seizures or those whose current medication regime is no longer effective enough.

Controlling Pain

Gabapentin is also an analgesic, meaning it providesrelief for chronic painandneuropathic pain. It’s most commonly used for the chronic pain associated with degenerative joint disease, such asarthritis.

It has also shown to be beneficial when used in combination with otherpain medications—such as nonsteroidal anti-inflammatories or opioids—to help with pain associated with surgery.

Easing Anxiety

Gabapentin can be used to help with anxiety in general, but specifically forthunderstorm phobiaor stress associated with vet visits. It likely decreases the release of excitatory neurotransmitters in the brain, which keeps anxiety from building up and gives the dog a more “chilled-out” feeling.

If your pup suffers from anxiety related to thunderstorms, vet visits, or other stressors, you can try using a Thundershirt® to help calm them. Your vet will help you determine if medication is necessary to treat your dog's anxiety.

What Are the Side Effects of Gabapentin in Dogs?

Sedation is the main potential side effect of gabapentin, and the level of sleepiness varies from patient to patient. Veterinarians will prescribe a starting dose, and if this results in the dog becoming a little too sedate, the veterinarian will taper the dose down to the most effective one.

Like all medications, there is a small chance that a dog could be allergic to it, in which case, this medication should be avoided. Gabapentin should also be used with caution in animals with kidney or liver disease, as it will take longer to metabolize.

What's the Gabapentin Dosage for Dogs?

The dosage range for gabapentin varies widely depending on what it’s being used to treat.

Gabapentin is available in several forms that are human-labeled products:

There is also an oral solution made at 250 mg/5 mL; however, sometimes the solution is formulated withxylitol, which isextremely toxic to dogs. Your veterinarian will help you order this medication in a form that is safe for your dog.

Sometimes a dog is too small to use the human formulations. If this is the case for your pet, acompounding pharmacycan formulate whichever form and dosage your veterinarian requests.

Gabapentin is usually given by mouth two to four times per day, with or without food. Check the directions on the bottle or ask your vet if you are not sure of the correct dosage for your dog.

Gabapentin should start to take effect fairly quickly, and relief should be noticed within one to two hours of administration. It’s a short-acting drug, and the effects will be gone in 24 hours. That said, the medication may last longer in dogs with kidney or liver impairment.

This drug should not be stopped abruptly when used to treat seizures, as it can result in withdrawal seizures.Always consult a veterinarian before discontinuing any medication.

Can You Use Gabapentin and Trazodone Together for Dogs?

Trazodoneis a commonly prescribed anti-anxiety medication frequently used to reduce stress before vet visits or during post-surgical confinement and rest. Gabapentin is often used for easing anxiety and pain in these situations, so these two medications are often prescribed together. Trazodone is safe to use with gabapentin.

Can Dogs Take CBD and Gabapentin?

If your pet is on gabapentin for pain (such as arthritis) or anxiety, you may also have been researchingCBD oil for your dog. It is not recommended to use these two together due to an increased risk of sedation.

Always consult with a veterinarian before starting your dog on any additional medications or supplements that were not originally prescribed to ensure that they are safe with your dog’s current medications.

Is Tramadol or Gabapentin Better for Dogs in Pain?

The pain medication tramadol is starting to fall out of favor with veterinarians.Studies have foundthat tramadol may not be as effective as originally thought. In fact, it was found to be ineffective at controlling pain associated with osteoarthritis in dogs. However, studies are ongoing, and the debate is still up for discussion on the effectiveness of tramadol.

In the meantime, veterinarians are turning more toward gabapentin for pain relief in their patients. However, your veterinarian may choose to use gabapentin in combination with other pain medications, including tramadol, for more effective pain management.

WRITTEN BY

Shelby Loos, DVM

Veterinarian

Dr. Shelby Loos is a 2017 graduate from the University of Florida with a certificate in aquatic animal medicine. After completing a year...

Gabapentin for Dogs: How It Can Help (2024)

FAQs

Gabapentin for Dogs: How It Can Help? ›

In humans, gabapentin is used to treat partial seizures, nerve pain, and restless leg syndrome. For dogs, it's used to treat seizures, anxiety, and nerve pain. It works by blocking calcium channels in the brain to suppress overly stimulated neurons that cause anxiety, nerve pain, and seizures.

What does gabapentin do for dogs? ›

Gabapentin is an anticonvulsant and analgesic drug that is commonly prescribed by veterinarians to treat pain, seizures, and anxiety in dogs. How gabapentin works is not completely understood; however, it is thought to block stimulation of the nerve cells.

How much gabapentin will calm a dog? ›

Gabapentin dose for dogs can vary, but usually, it is dosed at 5 to 30 mg/kg (or 2.2 to 13.6mg/lb) up to three times daily. Gabapentin can also be given before an anticipated stressful event, such as a veterinary visit, at a dose of 30-60 mg/kg one to two hours before the event.

What are the results of gabapentin for dogs? ›

One study of gabapentin for dogs with epilepsy found it decreased seizure activity in half of the test subjects. It can be used to help treat cats, too – a study on felines published by the American Veterinary Medical Association found that gabapentin helped control anxiety and compliance before stressful events.

What are the benefits of taking gabapentin? ›

Gabapentin is used to treat epilepsy. It's also taken for nerve pain, which can be caused by different conditions, including diabetes and shingles. Nerve pain can also happen after an injury. In epilepsy, it's thought that gabapentin stops seizures by reducing the abnormal electrical activity in the brain.

Can gabapentin cause a dog to not walk? ›

This could possibly cause hind leg weakness or trouble walking. If you notice your dog struggling to walk while on gabapentin, contact the vet for assistance.

Is gabapentin a very strong painkiller? ›

Official answer. Gabapentin is commonly used to treat some types of nerve pain but is classified as an anticonvulsant medicine, not as an opioid or painkiller.

Does gabapentin make dogs sleepy? ›

Gabapentin will make your pet feel calm and “chill.” The most often reported side effects of gabapentin in dogs are sleepiness and loss of coordination. The side effects can be worse the first time your pet takes it but generally go away within 24 hours. More rarely, your pet may experience vomiting and diarrhea.

How fast does gabapentin work in dogs? ›

Do not stop this medication abruptly in pets with epilepsy, as this can cause withdrawal seizures. This medication will take effect quickly, in about 1 to 2 hours, and improvement in clinical signs should follow.

When should you not give a dog gabapentin? ›

Higher doses may cause more sedation and problems with walking and balance. Careful use of gabapentin is important for dogs with significant liver or kidney disease. Gabapentin's effects may take longer to wear off for them. In addition, avoid use of gabapentin in pregnant and lactating dogs.

Why do vets give gabapentin? ›

Gabapentin is an anticonvulsant drug effective in humans to control neuropathic pain. In veterinary medicine, is extra-label used in combination with other treatments to control seizures when other drugs are not effective, when drugs are toxic, or for neuropathic pain treatment and anxiety.

Does gabapentin cause dogs to pee more? ›

Gabapentin might slightly increase urine retention in dogs, but this hasn't been well studied at this point. Occasionally, it also seems that urinary incontinence in dogs has improved on gabapentin. But it is unclear if this can be attributed to gabapentin or other factors.

Does gabapentin make dogs hungry? ›

The medication may help with weight gain or loss by increasing your dog's appetite. Some dogs predisposed to pickiness or decreased needs may start eating more when treated with this drug. Your dog might also eat more by simply sensing you're happier and less stressed with their new easy-going demeanor.

What is the biggest side effect of gabapentin? ›

This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors, such as feeling sad or hopeless, getting upset easily, or feeling nervous, restless, or hostile. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed.

What cannot be mixed with gabapentin? ›

Products that interact with gabapentin include:
  • Alcohol.
  • Antihistamine-containing cold, cough and allergy products.
  • Certain medicines for anxiety or sleep.
  • Certain medicines for depression, such as amitriptyline, fluoxetine and sertraline.
  • Certain medicines for seizures, such as phenobarbital and primidone.

What organ does gabapentin affect? ›

Gabapentin is a unique anticonvulsant that is used as adjunctive therapy in management of epilepsy and for neuropathic pain syndromes. Therapy with gabapentin is not associated with serum aminotransferase elevations, but several cases of clinically apparent liver injury from gabapentin have been reported.

How quickly does gabapentin take effect in dogs? ›

Do not stop this medication abruptly in pets with epilepsy, as this can cause withdrawal seizures. This medication will take effect quickly, in about 1 to 2 hours, and improvement in clinical signs should follow.

What is the most common side effect of gabapentin? ›

Dizziness and drowsiness are common side effects of gabapentin. Some other possible side effects include weight gain and trouble with movement.

Is gabapentin an anti-inflammatory? ›

Inflammation regulates ventricular remodeling after myocardial infarction (MI), and gabapentin exerts anti-inflammatory effects.

Is gabapentin a muscle relaxer? ›

Gabapentin is an anticonvulsive medication that received approval from the US Food and Drug Administration (FDA) in 1993 and has been available in generic form in the USA since 2004. Gabapentin was originally used as a muscle relaxant and an anti-spasmodic.

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