Methylcobalamin is the best-absorbed form of supplemental B12 in the body because it is bioactive. Bioactive simply means that the B12 has already been converted into a form that can be absorbed and used by the body’s cells immediately. Methylcobalamin requires little to no conversion and crosses easily through every part of B12’s metabolic pathway.
The chemical structure of methylcobalamin has a methyl group, which consists of a hydrogen and oxygen molecule. It’s this methyl group that makes it the most active form of Vitamin B12 in the body. It’s also the most common form of B12 found in animal-derived sources.
Methylcobalamin helps in synthesis of methionine and S-adenosylmethionine (SAMe). It is also required to maintain integrity of myelin, neuronal function, proper red blood cell formation and DNA synthesis. It may also help in lowering hom*ocysteine levels and reducing the risk of anemia.
